Download Clinical Applications of Capillary Electrophoresis (Methods by Stephen M. Palfrey PDF

By Stephen M. Palfrey

Stephen M. Palfrey brings jointly for first time a set of distinct capillary electrophoresis protocols designed completely for medical functions. Written via the major scientists who've usually perfected those tools of their personal laboratories, the protocols provide new and extra robust assays for plenty of regimen serum and blood checks now frequently played in medical laboratories, together with serum and urine proteins, hemoglobin separation, and the detection of CSF proteins, lipoproteins, myoglobin, cryoglobulins, and cathepsin D. The protocols provided for DNA research comprise double-stranded DNA research, the prenatal analysis of Down's syndrome, Rh D/d genotyping, the identity of mutated p53 oncogene, and the detection of microstaellite instability in cancers. a few of the tools will be computerized to interchange extra hard work in depth and dear exams which are at the moment utilized in such a lot medical laboratories. medical functions of Capillary Electrophoresis demonstrates truly the simplicity, versatility, and tool of CE over traditional equipment.

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Extra info for Clinical Applications of Capillary Electrophoresis (Methods in Molecular Medicine)

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In rare cases, the band in the urine may be caused by the opposite light chain, but this is highly unusual. References 1. , et al. (1987) Multiple myeloma and severe renal failure: A clinico-pathologic study of outcome and prognosis in 34 patients. Medicine (Baltimore) 66, 126–137. 2. Johnson, W. , Kyle, R. , and Pineda, A. A. (1990) Treatment of renal failure associated with multiple myeloma: plasmaphoreresis, hemodialysis, and chemotherapy. Arch. Intern. Med. 150, 863–869. 28 Jenkins 3. , and Dixon, D.

1972) Agarose gel electrophoresis. Scand. J. Clin. Lab. Invest. 29 (Suppl 124), 7–19. 5. Gordon, M. , Arias, A. , and Zare, R. N. (1991) Protocol for resolving protein mixtures in capillary zone electrophoresis. Anal. Chem. 63, 69–72. 6. -T. , and Sternberg, J. C. (1991) Capillary electrophoresis—a new clinical tool. Clin. Chem. 37, 14–19. 7. Kim, J. , Park, J. , Park, J. , Doh, H. , Heo, G. -J. (1993) Quantitative analysis of serum proteins separated by capillary electrophoresis. Clin. Chem. 39,689–692.

1996) Application of capillary electrophoresis in clinical chemistry: developments from preliminary trials to routine analysis. J. Capillary Electrophoresis 3, 89–110. 11. Jenkins, M. , Martin, H. , and Guerin, M. D. (1995) Evaluation of serum protein separation by capillary electrophoresis: prospective analysis of 1000 specimens. J. Chromatogr. B. 672, 241–251. 12. Jenkins, M. A. and Guerin, M. D. (1996) Optimization of serum protein separation by capillary electrophoresis. Clin. Chem. 42, 1886.

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